alpha-氨基-gamma-丁内酯 氢溴酸
Alpha-Amino-Gamma-butyrolactone hydrobromide
CAS: 6305-38-0
Molecular Formula: C4H8BrNO2
alpha-氨基-gamma-丁内酯 氢溴酸 - Names and Identifiers
alpha-氨基-gamma-丁内酯 氢溴酸 - Physico-chemical Properties
| Molecular Formula | C4H8BrNO2 |
| Molar Mass | 182.02 |
| Melting Point | 220-225°C(lit.) |
| Water Solubility | almost transparency |
| Appearance | Crystalline Powder |
| Color | White to light beige |
| BRN | 4530084 |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
alpha-氨基-gamma-丁内酯 氢溴酸 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29322985 |
alpha-氨基-gamma-丁内酯 氢溴酸 - Introduction
Alpha-Amino-Gamma-butyrolactone hydrobromide, also known as Alpha-Amino-Gamma-butyrolactone hydrobromide, has the chemical formula C4H8NO2 HBr.
Nature:
1. Appearance is white or white crystalline powder;
2. can be dissolved in water, and poor solubility in ethanol, ether and other organic solvents;
3. It is an inorganic salt with relatively stable chemical properties.
Use:
Alpha-Amino-Gamma-butyrolactone hydrobromide are mainly used in the field of organic synthesis, often as intermediates in drug synthesis. It is often used in the preparation of other organic compounds or drugs, such as the synthetic antipsychotic drug morphine (Matipitol).
Preparation Method:
Alpha-Amino-Gamma-butyrolactone hydrobromide can be prepared by the following steps:
1. reacting γ-butyrolactone with propionyl chloride to obtain butyrolactone acid;
2. reacting butyrolactone acid with carbon monoxide and ammonia in the presence of a catalyst to obtain α-amino-γ-butyrolactone;
3. reacting α-amino-γ-butyrolactone with hydrochloric acid to produce chloride;
4. Chloride reacts with hydrobromic acid to obtain Alpha-Amino-Gamma-butyrolactone hydrobromide.
Safety Information:
Alpha-Amino-Gamma-butyrolactone hydrobromide are chemicals, the use should pay attention to the following safety matters:
1. avoid inhalation of dust or contact with skin and eyes to prevent irritation;
2. in use and operation, should wear personal protective equipment, such as gloves, goggles and protective clothing, etc;
3. storage should be placed in a dry, cool place, and away from fire and sparks.
When using and handling, it is necessary to comply with relevant safety operation procedures and take protective measures according to the actual situation.
Nature:
1. Appearance is white or white crystalline powder;
2. can be dissolved in water, and poor solubility in ethanol, ether and other organic solvents;
3. It is an inorganic salt with relatively stable chemical properties.
Use:
Alpha-Amino-Gamma-butyrolactone hydrobromide are mainly used in the field of organic synthesis, often as intermediates in drug synthesis. It is often used in the preparation of other organic compounds or drugs, such as the synthetic antipsychotic drug morphine (Matipitol).
Preparation Method:
Alpha-Amino-Gamma-butyrolactone hydrobromide can be prepared by the following steps:
1. reacting γ-butyrolactone with propionyl chloride to obtain butyrolactone acid;
2. reacting butyrolactone acid with carbon monoxide and ammonia in the presence of a catalyst to obtain α-amino-γ-butyrolactone;
3. reacting α-amino-γ-butyrolactone with hydrochloric acid to produce chloride;
4. Chloride reacts with hydrobromic acid to obtain Alpha-Amino-Gamma-butyrolactone hydrobromide.
Safety Information:
Alpha-Amino-Gamma-butyrolactone hydrobromide are chemicals, the use should pay attention to the following safety matters:
1. avoid inhalation of dust or contact with skin and eyes to prevent irritation;
2. in use and operation, should wear personal protective equipment, such as gloves, goggles and protective clothing, etc;
3. storage should be placed in a dry, cool place, and away from fire and sparks.
When using and handling, it is necessary to comply with relevant safety operation procedures and take protective measures according to the actual situation.
Last Update：2024-04-09 02:00:47
